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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLTF
All Species:
4.55
Human Site:
T843
Identified Species:
7.69
UniProt:
Q14527
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14527
NP_003062.2
1009
113929
T843
N
A
L
M
H
A
L
T
D
L
R
K
K
N
P
Chimpanzee
Pan troglodytes
XP_001138277
1009
113822
T843
N
A
L
M
H
A
L
T
D
L
R
K
K
N
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534300
1106
124184
I940
N
A
L
M
H
A
L
I
D
L
R
K
K
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCN7
1003
113298
I837
N
A
L
M
H
A
L
I
E
L
R
T
K
D
P
Rat
Rattus norvegicus
NP_001099948
974
110023
I808
N
A
L
M
N
A
L
I
E
L
R
T
K
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508504
884
99044
K747
S
L
I
E
K
P
L
K
E
S
G
F
V
F
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090145
999
112576
V833
S
A
L
M
H
S
L
V
E
Q
R
R
K
D
A
Zebra Danio
Brachydanio rerio
XP_693071
942
104740
L778
L
A
L
M
S
N
L
L
K
L
R
N
E
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
K900
N
M
V
I
Q
I
L
K
T
S
I
L
K
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786706
1093
121576
L922
D
A
L
M
E
C
L
L
T
E
R
A
A
D
K
Poplar Tree
Populus trichocarpa
XP_002308876
799
88908
P662
M
L
V
L
L
E
E
P
L
K
E
A
G
F
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF61
881
98598
P744
M
L
L
L
L
E
T
P
L
K
A
A
G
F
T
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
V653
F
T
S
M
L
D
L
V
E
W
R
L
K
R
A
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
R1060
V
A
L
I
S
H
L
R
T
L
R
Q
E
H
P
Conservation
Percent
Protein Identity:
100
99.5
N.A.
85.5
N.A.
83.6
81.4
N.A.
71.7
N.A.
64.3
53.1
N.A.
21.1
N.A.
N.A.
34.5
Protein Similarity:
100
99.8
N.A.
88
N.A.
89.7
87.9
N.A.
78.5
N.A.
79.3
69.8
N.A.
41.2
N.A.
N.A.
53.1
P-Site Identity:
100
100
N.A.
93.3
N.A.
73.3
66.6
N.A.
6.6
N.A.
46.6
46.6
N.A.
20
N.A.
N.A.
33.3
P-Site Similarity:
100
100
N.A.
93.3
N.A.
86.6
86.6
N.A.
26.6
N.A.
80
60
N.A.
40
N.A.
N.A.
46.6
Percent
Protein Identity:
33.6
N.A.
N.A.
36
22.7
25.2
Protein Similarity:
50.4
N.A.
N.A.
52.7
40.9
43.9
P-Site Identity:
0
N.A.
N.A.
6.6
26.6
40
P-Site Similarity:
13.3
N.A.
N.A.
13.3
33.3
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
65
0
0
0
36
0
0
0
0
8
22
8
0
15
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
0
0
22
0
0
0
0
36
0
% D
% Glu:
0
0
0
8
8
15
8
0
36
8
8
0
15
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
8
0
22
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
15
0
0
% G
% His:
0
0
0
0
36
8
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
8
15
0
8
0
22
0
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
15
8
15
0
22
58
0
15
% K
% Leu:
8
22
72
15
22
0
86
15
15
50
0
15
0
0
0
% L
% Met:
15
8
0
65
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
43
0
0
0
8
8
0
0
0
0
0
8
0
22
0
% N
% Pro:
0
0
0
0
0
8
0
15
0
0
0
0
0
0
50
% P
% Gln:
0
0
0
0
8
0
0
0
0
8
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
72
8
0
8
0
% R
% Ser:
15
0
8
0
15
8
0
0
0
15
0
0
0
8
8
% S
% Thr:
0
8
0
0
0
0
8
15
22
0
0
15
0
0
15
% T
% Val:
8
0
15
0
0
0
0
15
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _